Discovery and Development of the CRISPR-Cas Genome Editing Technology

Friday, February 12, 2016: 1:00 PM-2:30 PM
Marriott Balcony B (Marriott Wardman Park)
The recent discovery of a bacterial immunity process and its associated enzymes (CRISPR-Cas) has enabled a powerful, yet remarkably simple, genome editing technology that has quickly been put to use worldwide. Scientists are now able to program the CRISPR-Cas to selectively delete or alter almost any site within a complicated genome. The CRISPR-Cas-based genome editing technology has transformed the method of genetic material manipulation and will have profound impacts on our society. As interest in broadening CRISPR-Cas applications grows in areas of gene therapy, sustainable food supply, and even human enhancement, increased understanding of the fundamentals of the CRISPR-Cas biology and biochemistry is needed. Leaders of CRISPR-Cas research present the most recent findings on the mechanism of CRISPR-Cas enzymes and efforts to improve the specificity, and thereby the safety, of the technology.
Hong Li, Florida State University
Emmanuelle Charpentier, Max Planck Institute for Infection Biology
The Transformative CRISPR-Cas9 Genome Editing Tool: Lessons Learned from Bacteria
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