The Large Hadron Collider (LHC) stands on the brink of unveiling the next layer beyond the current standard model of particle physics. It stands as the crowning achievement in international scientific collaboration, resulting from the efforts of CERN and its 20 European member states, coupled with crucial contributions from an additional 20 countries from around the world. Particle physicists are already planning the next facility — either an electron-positron linear collider or an energy, luminosity upgrade to the LHC — that will be needed to capitalize on the LHC's discoveries. However, the next project, likely a significant step beyond the LHC, will require a new form of global partnership to become a reality. This panel will discuss the efforts that are underway to produce a viable model for cooperation on a hitherto unrealized scale. Particle physics is not the only science facing these tough questions about global participation, cooperation, and coordination. As other disciplines tackle their key scientific questions at a global level, these issues — and their solutions — will become even more important.