Global Fisheries and Food Supply Studies of marine ecosystems indicate that services essential to humans have been diminished and future ecosystem sustainability is endangered by exploitation patterns commonly practiced around the globe. A global effort is underway to strengthen the robustness and resiliency of large marine ecosystems (LMEs). The world’s LMEs annually produce 80 percent of the yields from marine fisheries and contribute $12.6 trillion to the global economy. LMEs are national and regional centers of coastal pollution, acidification, nutrient over-enrichment, overfishing, habitat degradation and biodiversity loss -- contributing to the diminished resilience and robustness of coastal ocean services. A five-module, science-based strategy is being applied to enhance the health of LMEs in 110 economically emerging countries in Africa, Asia, Latin America, and Eastern Europe. The countries are implementing projects for protecting ecosystems as they move toward the sustainable development of goods and services in 17 LMEs along the coasts of Africa, Asia, and Latin America. They are being assisted in this effort with $4.1 billion in financial support mobilized through grants, investments, and co-financing funds from the Global Environment Facility and the World Bank and focused governance actions predicated on science-based assessments of the changing ecosystem conditions. Participating countries are turning the corner from degradation trends toward sustainable development of LME goods and services.