The public's acceptance of nuclear power has increased in recent years. However, several issues remain that, in the mind of the public and policy-makers, still present significant barriers to the further penetration of nuclear energy into the global marketplace. Among these, the most prominent are safety, sustainability, nuclear waste, and nuclear proliferation. Recently, concepts have been advanced that, if technically and commercially feasible, would greatly mitigate many, if not all, of these concerns. These concepts range from the creation of international nuclear fuel banks and waste disposal sites to potentially game-changing, disruptive technologies such as traveling wave reactors and hybrid fusion-fission energy schemes. This symposium will explore the technical feasibility of such advanced concepts as well as the societal and global policy implications of these schemes. A moderated panel discussion of global energy and nuclear power experts will explore the gaps in making these technologies a reality and key steps required to make progress toward safe, sustainable nuclear energy that minimizes nuclear waste disposal and nuclear proliferation concerns.