Discontinuous Genes and Regulation of Higher Eukaryotic Gene Expression

Saturday, February 18, 2017: 10:00 AM-11:30 AM
Room 309 (Hynes Convention Center)
Louise Chow, University of Alabama, Birmingham, AL
Using EM, I and collaborators discovered RNA splicing in adenoviruses in 1977. We also described how alternative RNA splicing, alternative poly-A sites, and alternative promoters expand genetic capacity and versatility. These principles in regulating gene expression initially received little attention but were “rediscovered” as being crucial to higher eukaryotes. As a reserved foreign woman scientist, I was not accorded recognition commensurate with these revolutionary discoveries. Proper credit remains a touchy issue for budding scientists.