2016 AAAS Annual Meeting (February 11-15, 2016)

February 10 - 15, 2016

New and Emerging Tobacco Products: Biomarkers of Exposure and Injury

On June 22, 2009, the Family Smoking Prevention and Tobacco Control Act was signed into law, giving the U.S. Food and Drug Administration (FDA) the authority to regulate new and emerging tobacco-derived products. Subsequently there was an obvious need for scientific data to inform FDA’s decision-making about these products. Studies on biomarkers of exposure and injury, and controlled, acute, chronic, and longitudinal exposure studies are being conducted to better define what new and emerging tobacco-derived products do in a variety of preclinical and clinical settings. New and emerging tobacco- and nicotine-derived products now come in a dizzying array of forms – including electronic cigarettes, smokeless tobacco (e.g., snus, snuff, gutkha), shisha for hookah/water pipes, dissolvable lozenges, and nicotine gels –  that contain, deliver, or generate varying amounts of harmful or potentially harmful constituents, making it challenging to predict the biological effects of exposures based solely on traditional cigarette exposure studies. This symposium provides a broad overview of research to identify biomarkers of exposure, biomarkers of injury, and acute and chronic effects in the cardiovascular, pulmonary, and reproductive organ systems resulting from exposure to new and emerging tobacco products.