The International Space Station (ISS) is a unique, multidisciplinary laboratory where the scientific endeavors of 68 countries have found their footholds in space research for the betterment of human exploration and the betterment of life on Earth. This symposium brings together expert investigators from varied research fields currently studied onboard the ISS who are engaged in investigations requiring international coordination and collaboration. The panelists will share with the community their experiences in leading these investigations, working with international teams, and some of the exciting new results from their research programs. A one-hour moderated discussion with ISS program scientists will be provided after the panelists complete their presentations