Refactoring Nitrogen Fixation

Saturday, 15 February 2014
Regency B (Hyatt Regency Chicago)
Christopher A. Voigt , Massachusetts Institute of Technology, Cambridge, MA
Many chemical transformations of interest to industry can already be achieved by living systems with low energy input. However, these functions are often complex and difficult to transplant into heterologous systems. One important example is nitrogen fixation, which is a key process with respect agriculture and the production of ammonia thus consumes a large amount of energy each year. This talk will cover recent advances in refactoring the genetic cluster that encodes this function so that it can be engineered into new cell types.