Challenges and Approaches for Mosquito-Targeted Disease Control

The control of mosquito vector-borne diseases such as malaria, dengue and yellow fever has until today mostly been achieved by targeting the mosquito. Current efforts have however, despite their efficacy, proven to be insufficient at a global scale. The genome era has brought new knowledge and tools to scientists around the world for the discovery of ways to intervene with the mosquito’s capacity to transmit deadly pathogens among humans.  Past and current vector targeted disease control strategies will be addressed along with perspectives on future approaches based on the genomic revolution.